P-182 ANALYSIS OF 3-HYDROXYGLUTARIC ACID IN DRIED URINE SPOTS BY LC-MS/MS; APPLICATION FOR THE DIAGNOSIS OF GLUTARIC ACIDURIA TYPE 1 2011
Background: Accumulation of 3-hydroxyglutaric acid (3HGA) in body fluids is pathognomonic for type 1 Glutaric Aciduria (GA1). To date, methods for quantification of 3HGA mainly involve complex analyses using stable isotope dilution gas chromatography mass spectrometry (GC/MS). Here, we describe a simple liquid chromatography tandem...
27 septiembre, 2022
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